OsoPopoToto 

a Soyboy reaction to seeing something cute and then getting weird faces from people.

look at that doggie OsoPopoToto (too far WeirdChamp)

OsoPopoToto by Awl1 December 11, 2019

OSOGOF 

OH SHIT, OH GOD, OH FUCK

Person 1: "Hey Is this arena good for the plantera boss fight"
Person 2: "Nah you're missing an OSOGOF tunnel for when she goes into her second phase
Or
Person 1 over text: "Hey your mom found out about you smoking and is waiting for you to come home
Person 2 over text: "OSOGOF

OSOGOF by Imacae May 5, 2022

Osokin 

An incredibly large penis. Exceding all other penises by a large margin.

"Mam, Duffman's Osokin is way larger than DirtyJoses."

Osokin by Duffman November 18, 2004

Osomatsu 

Osomatsu is a eldest brother of the sextuplets of the anime Osomatsu-san. He is famous for playing pachinko, being silly, rubbing his nose with his finger and doing the money sign with his hand. He acts like the leader sometimes but he is actually a cute dork. He usually wears a red jumper and jeans.

Person 1: Who is ur fave Matsuno brother?
Person 2: I love Osomatsu!

Osomatsu by Breanime145 August 9, 2017

Osob 

Osob is a very nice person. She hardly gets angry but beware because if she does you will regret it greatly. She is a great person to be around and once you get to know her and become her close friend you will learn she is extremely loyal and you will be friends for life.

Girl 1: Did you meet Osob today?
Girl 2: Yeah she seems great!

Osob by .yuhh November 24, 2019

Osomatsu-san

The mind-fukery of an anime that came out in 2015.
English name:: Mr.Osomatsu
To celebrate Akatsuka Fujio's 80th birthday, Osomatsu-san continued the adventures of the Matsuno sextuplets from Akatsuka-sensei's manga and anime Osomatsu-kun.
As for its contents, Osomatsu-san is about the Matsuno sextuplets' lives as twenty-something virgin NEETs. Interesting right?

First you have the "miraculous idiot" Osomatsu, then the "cool idiot" Karamatsu, the "reasonable idiot" Choromatsu, the "pitch-black idiot" Ichimatsu, the "of-another-dimention idiot" Jyushimatsu, and finally the "good-at-letting-others-pamper-him" idiot Todomatsu.
Episode count(not including extras):: 25
Genre(ep1-23 & 25)::Comedy. Episode 24::Suffering

This anime that was thought to be one of those that would just slip under everyone's radars and be "that one anime that I never got to watching" is now one of the most popular anime in Japan. So y'know...why don't ya go watch it?

Osomatsu-san is an anime.
I honestly don't know what sentences you would use Osomatsu-san in.

Osomatsu-san by Ichimat June 16, 2017

osok 

one shot one kill; when it takes only one shot to kill the other guy. usually used in first person shooter games such as cs

i osok'd him with a deagle to the face

osok by koreanknife January 11, 2005