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Let's go back to the hotel and pop off some. I got a lil' Hennessy up there, some Don P.
pop off by BDB January 2, 2005
to pop an illegal pill (A drug)
Imma pop off this ecstasy before we go in the club!
pop off by meat rack January 23, 2008
"We could pop off on this"
Pop Off by SophiG June 1, 2018
Cheap liquor. Tastes and smells like rubbing alchlohol. Real easy to get drunk with.
Girl: can i have some?
Guy: yeah sure.
Girl: uugh! what is that?
Guy: pop off.

SHit, pass tha pop off. I can't feel my legs!
pop off by Coach Pfeff August 14, 2006
Post Office Protocols off
We are looking forward to the end of our round delivering letters with the Royal Mail and to having a bit of fun with our computers, so you can pop off
1. Telling someone to go away, usually used aggressively

2. Fighting someone

3. Telling someone to rant

4. Telling someone to calm down
1. Pop Off my twitter feed sis

2. I'm about to pop off on you sis

3. He broke up with you? Pop off sis

4. Hey pop off sis! It's all good!
Pop Off by ben ben bo en August 31, 2018