Itachi 

One of a baddest ninjas on Naruto. He is a older brother of Sasuke Uchiha, once a prodigy of the Uchiha Clan who rose in ninja ranks at early age. He friggin killed his own clan for some unknown reasons, probably to motivate his envious brother to grow stronger and be a threat to his awesomeness. He left Konoha and join an criminal organization Akatsuki. He's partners with S-Criminal of Water Country Kisame Hoshigake. His ninja skills are cool, with his sharighan, he can copy ninjutsu, taijutsu, and genjustu and send it back to his opponents. With his Mangekyo Sharigan, He can send his foes to a illusionary world and torture them for 72 years, mentally crippled Sasuke and Kakashi. With his sharighan, He could be God-like Invisible Ninja.

Itachi's qoutes.
# You're not even worth killing.
# Foolish little brother. If you want to kill me, hate me, detest me, and survive in an unslightly way. Run, run and cling to life. And then some day, when you have the same eyes as I do, come before me.
# You're still too weak. You don't have enough hate. And you know something? You never will.
# Indeed, your abilities are impressive. They might even be enough to resist the Mangekyo Sharingan. However, there is something they can't defend against: This special Sharingan jutsu called "Tsukuyomi." Only someone with the Sharingan and Kekkei Genkai can defeat me.
# Why is it that the Uchiha clan was known by all and feared by all? I'll show you what the Sharingan can do when it's wielded by a true heir of the bloodline.

Itachi by MUKIZA July 24, 2007

itachi 

A cold-hearted, ruthless killer from the anime series Naruto who, at the age of thirteen, thought it necessary to murder nearly his entire clan and mentally scar his then eight-year-old brother Sasuke in the process---all in order to “test his capacity.”

Generally despised by Sasuke fans.

Generally worshipped by those who believe his sadistic tendency to put people through horrific mental torture is “badass” or “cool.”

Also means "weasel" in Japanese.

Itachi is one sadistic ninja.

itachi by Kathryn "Innocent Sacred" September 8, 2008

Itachi 

The most overrated piece of shit in anime, whenever someone brings up strong Naruto characters he has to be in the discussion. Even though he’s fodder compared to Madara, Obito, Naruto, Sasuke and pretty much the rest of the main protagonists and antagonists.

Weeb 1: Bro who’s the strongest Naruto character
Weeb 2: iTaChi! iT hAs tO bE iTacHi!

Itachi by Blackpeoplestink99 May 23, 2020

Itachi 

Weasel, literal meaning (appropriate in my opinion)

He is such an Itachi

Itachi by Karralmer July 28, 2010

Itachi 

Uchiha Itachi is the other brother of Uchiha Sasuke. He is a "missing" S Class ninja and also a member of The Akatsuki, where his partner is the "famous" shark-man Kisame (Weilder of the Samehada). Uchiha Itachi murdered his best friend in order to obtain the Mangekyou Sharingan. Uchiha Itachi then murdered the entire Uchiha clan except for his younger brother Uchiha Sasuke. The reason for that is so that Sasuke could become strong enough to kill Uchiha Itachi.
The Japanese word "itachi" literally means "weasel." In which most people often make fun of Uchiha Itachi for that reason.

Itachi is usually interpreted as a femal or a transvestite. And a homosexual.

Itachi by iDeidara April 1, 2007

itachi 

A female Japanese insult, loosely translated as "Masculine Female"

"Look at that Itachi!"
"Sasuke's brother?"
"No! I was refering to Sakura!"

itachi by Makaze June 9, 2008

Itachi 

A blind, ded hobo from the manga series, Naruto.

Itachi is the first spawn of the Uchiha clan head. He is immediately recognized as a 'genius', amazingly skilled at ninja fighting/tactical abilities across the board, despite very little canonical evidence of this. Fugaku mostly ignores Itachi's little brother in favor of Itachi, which is ironic since generally it's the scorned child that goes and offs everyone.

Which is what Itachi did, incidentally, then he was busy being a troubled teen.

Shortly after the death of the Third Hokage, roughly five years later, Itachi returns to Konoha, this time under the organization, Akatsuki, and in pursuit of Naruto. Itachi's little brother is understandably incensed by Itachi's reappearance; he challenges him and gets PWN'd.

Thereafter, Itachi makes numerous random appearances, to no particular avail. He is apparently going blind, which makes it even more sad, because it's obvious he's never been to a seamstress in his life, and all of his clothes fit him like run-over shopping bags.

Then he dies.

1. Look, there goes Itachi. His brother is in the other direction, but take pity on the poor lump.

2. Itachi kills lots of people, including himself.

Itachi by Kalliel March 21, 2009