Anti-Matter Suppository Capsule (AMSC) 

A devise one must insert into their rectum upon learning the secret of the space-time continuum, whereby the mental energy required to process these thoughts outweighs that of gravity itself; and creates an unstable void in our very universe. The anti-matter suppository capsule combats this with copious amounts of radiation.

*smoking weed alone in basement:

hits large bowl; *thinks about the origins of the universe

*universe begins to impode upon itself
*sticks Anti-Matter Suppository Capsule (AMSC) in rectum
*all is as it was... except now incredibly high

Anti-Matter Suppository Capsule (AMSC) by xavier wells June 12, 2012

midol suppository 

an imaginary pharmaceutical item that is used to imply a person is being a lame ass, pussy bitch, or suffering from PMS like symptoms.

Tyler: Man Jon is being a big pussy, he says he can't play Halo because his head hurts and he's tired.
Tate: Wow, sounds like he could use a midol suppository for sure.

midol suppository by midol man May 18, 2013

signal suppository 

n. A driver who accelerates when you signal to change into their lane, even though they have a lot of space to let you in. Very common in Los Angeles driving. Seeing your turn signal, they instinctually step on the gas, and get right up your a**, like a suppository.

I almost had a bad accident because I changed lanes and that signal suppository nearly rammed into me!

It's so hard to change lanes because of these signal suppositories!

signal suppository by Doctor Science February 20, 2011

chilean Suppository 

The rescue pod used to retrieve the 33 miners in Chile; that resembles a giant suppository.

If I was trapped in a mine, I don't think I could be rescued with the chilean Suppository, I'm too fat.

chilean Suppository by superkustom October 15, 2010

Script Suppository 

Generally used by high-level programmers, particularly SAV and DHCP specialists; a place where scripts and code are stored for later use. Can contain injectable code of any type, sometimes used for penetration testing on enterprise systems.

I reached deep into my script suppository and extracted a nugget of VB perfection.

Script Suppository by Kommodore March 20, 2009

Mexican suppository

Shoving a Carolina Reaper pepper up one's ass. This act will probably not be performed in a sober condition, perhaps on a dare.

Dave got wasted and tried a Mexican suppository last night. He should be out of the hospital in a day or two.

Mexican suppository by Huge Assman November 1, 2017

Cascade suppository challenge 

The act of inserting a Cascade tablet up one's ass.

Damn man, I've never been drunk enough to do the Cascade Suppository Challenge!

Cascade suppository challenge by J.R. 1 September 24, 2021