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Internet slang for "laugh my poop out", it can be used figuratively or literally.
You did WHAT to your grandmother?!? lmpo.
lmpo by Prima B. Goode July 23, 2004
The joke he told seriously made me LMPO
LMPO by PeacePrincess November 15, 2011
Laughing my piss out. Came from laughing my ass off.
Nerd: OMFG THAT NEW POKEMON CARD IS KEWL!
Kid: Pokemon is crap, lmpo.
lmpo by JordanM February 11, 2005
LAUGH MY PENIS OFF

you laugh so hard that your penis falls off

:(

sadd ass
OMG OMG that was so funny i LMPO
LMPO by x-alice-x April 29, 2008
A Less Explicit Sounding Way to Say Lick My Pussy Off
Guy; Hey Dude you Kayla ask me to LMPO And if i did she would Suck my dick

Guy Friend;Damn that's a hard choice LMPO so she could suck my wood
LMPO by 1marvin February 5, 2012
Laughing my posterior off

The classy version of lmao
Robert: Oh Charles, I am just oozing money! I am so rich, it's funny!

Charles: Good show, Robert, good show! lmpo!
lmpo by ChigglyWiggly November 12, 2012