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To take shots or drink any alcoholic beverage, mainly vodka/liquor to the point you are atleast tipsy.
Yo, its thirsty thursday and we got drinks on deck. That means its time to get Wet Up! Holla Atcha Gwalla
Wet Up by TeddiGraham March 2, 2010
To be shot up stabbed resulting in death.
Man Marcus was stuntin on some bangsta last night and got wet up.
wet up by Young Ceize September 7, 2005
to be soaked and drenched in your own blood due to gunshots or stab wounds
i heard someone got "wet up" at the ghetto club uptown last night.
wet up by JakeJohn August 10, 2012
To verbally outline your excited emotion whilst hang gliding!
Hahaha did you hear Wilson yelp 'Wet up' as he landed?!?!
Wet up by Wilson_fly August 25, 2010
Shoot him up
I'm about to Wet up a nigga

Let's go and wet someone up right now
Wet up by Gxd-clader December 28, 2021

Wet up the block 

1. A drive by shooting where multiple shots are fired
2. To arouse a group of girls solely based on your appearance and suave
1. In the studio...

21 Savage: Wet yo mama house, wet yo grandma house, keep shooting till somebody die

Metro Boomin: Yo! That was bars bro! Did you really Wet up the block?

21 Savage: Hell ya! I'm a real street nigga, bitch, i am not one of these niggas bangin' on wax

2. Rachael: Did you see Joey's haircut?

Monica: Yes I did! He's such a beautiful man

Rachael: I know! He had all those girls going crazy, literally trembling to there knees

Monica: Yup! He really Wet up the block!