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g's up hoes down 

Your boys are first priority.G's up. Hoes are second. Hoes down
g's up hoes down by Sloppeeman December 20, 2006

G's up, Ho's down 

This comes from the streets, man! Often referred to in rap songs. It indicates the need to have the gangsters "up" or on top of things, and keep the Ho's (bitches) down. Thought to have originated from pimps who would say it to indicate their whores were on their backs making the money for the pimps. Often said when greeting a fellow G, or upon entering a room or party. Meant to re-assure
G1: Greetings. G's up, ho's down.
G2: Fo' shizzle, ma' nizzle. Word.
G's up, Ho's down by Gacis June 2, 2004

g's up hoes down 

Type of Mdma aka Ecstasy popular on the east coast (especially Georgia and south Florida.

Its supposed larger dose of mdma causes it to be more expensive than "normal E"

Example prices of a city in south florida:
Regular E: $15 Each
Gs up: $20 Each
Yo man got some beans?
Fuck ya man I got some g's up hoes down lets roll on this shit
g's up hoes down by Sn1p3r June 24, 2007

G's up, Ho's down 

Bangin ass ecstasy pills
popular in jersey
u got sum G's up, Ho's down ma nigga?
G's up, Ho's down by munx March 30, 2007

G's up, Ho's down 

Ecstasy pills with the letter G with a dot on one side and a chick on the other. If you in Jersey and got this be aware that it is most likely MDA, not MDMA. Check MDA out on erowid and check ecstacyinfo.org (search for "g" and you'll see and entry for Newark, NJ which says it was tested positive for MDA).
"The dance is Saturday and I just got hooked up with some G's up, ho's down."

G's up, Ho's down  

G's up, hoes down, while you motherfuckers bounce to this

snoop doggy dogg-Gin and juice
G's up, Ho's down