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Generally some stupid person. An alternative insult to words like Clegghead, plonker or jebend.

Derived from the word shizzle.
Bob Cheel...you are a shizzo!
Shizzo by and the Hams November 25, 2007
Related Words
A phrase used to describe singer and songwriter Lizzo. The 'sh' signifies that she is a shnack and can also replace the first letter of somebody's first name. It is also an old fashion way of saying 'she's old' a.k.a 'that woman is shizzo'
example: That woman is shizzo... or How schamazing is that dress
OR
Hello my name is Brandon - Hello my name is Shrandon (replace the B with Sh)...
Shizzo by IsThatBrandon January 3, 2020
noun
A term of endearment to describe a friend or partner.
I enjoy hanging out with my shizzos it's great fun
Shizzo by the real shizzo February 5, 2024
A substitution for mate. commonly used as a term of endearment
I love hanging out with my shizzo's
Shizzo by the real shizzo February 5, 2024

fo' shizzo bizzo 

ur all wrong it means....for sure brother-meanin friend not literal bro.
"can you help?"
"fo' shizzo bizzo"
fo' shizzo bizzo by yoyo June 8, 2004
an abbreviated use of fo shizzo my nizzle (or whatever). to be sure. valley girl lingo: for sure
Q. "do you want to have sex with me?"
A. "fo shizzo."
fo shizzo by conneca September 20, 2003