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1. A phrase said between people before a competitive event. Usually followed by Giving Skin.
2. A British comedy much loved by many people.
1. You're going down. Game On.
2. "Help! I've got my knob stuck in the vacuum."
Game On by Kip Stevens April 22, 2004
What is said by people who think they can do better at something than somebody else.
Mike: I can run fater than you.
George: No you can't.
Mike: Game on.
Game On by whenbettercomes August 10, 2012
1. A term used during a game that has been interrupted to signalling time to continue. Often preceded by the term CAR and here in Canada at least usually used during street hockey.

2. A term used by an individual who has been given a challenge or seen someone do something that they plan to put do them at, at any cost.
1. After the car drove by buddy yelled game on and we got the goals back on the street and continued playing.

2.Buddy just said nobody could possibly change a tire faster than him so I said game on man!
Game on by Broodyfour October 16, 2017
"Did your interview go well?"
"GAME ON, BITCH!"
game on by Showstopper February 18, 2005
It's been game on since I got to the office this morning.
game on by coloradoeyes April 18, 2010
When you have slept repeatedly with your friend’s ex bf.

She was seeing 5 other guys at the time and he meant nothing to her.

She called you drunk to meet at a bar to cock- block him.

You hit it off with him too much and went home with him.

The hook-up relationship continues for weeks after he told you he has no feelings, but always texts you back right away.

You have to see him at work on Monday and don’t know whether to ignore him or not.

So you text him to give him a ‘heads up’
and he responds right away and says

“IDK, be polite”
And you respond...okay ....”Game On!”
Game On by Billy-Soo January 19, 2020