An expression of despair, disgust, or general dissatisfaction.
(Upon spotting a flat tire on your car when emerging from the last showing at a movie theater on a very rainy Saturday night): "Well, fuck me naked and hide my clothes!"
Having plans cancelled at the last minute. Usually occurs when the person with whom you had plans gets a better offer, or is too tired/hungover/grouchy/pissed off at you to want to hook up.
I was going to have dinner with my homie, but he was too sleepy to go so he rainchecked me.
A general feeling of unease or vague anxiety, usually caused by mildly to moderately awkward social situations and sometimes involving inappropriate or unwanted displays of affection among persons whom are young or unfamiliar.
"Did you see that guy making kissy faces at me over there?"
"Yeah, he's creepy... he gives me the heeby-jeebies!"
"Can you believe those two? They're only in sixth grade!"
"Word. They're a little young for that... it kinda gives me the heeby-jeebies."