Frantic and compuslive behaviour often associated with methamphetamine abuse (crank). People who regularly abuse crank may find themselves unable to stop a particular random activity like searching drawers, having sex, or putting things apart. This is called tweaking.

High on meth/crank. See also "Smebbin".

1. To be under the effects of amphetamines, esp. crystal methamphetamine hydrochloride.

2. To be nervous or worried about something, esp. the presence of law-enforcement personnel.

To describe someone that is out of thier mind or making a mistake.

To do crack or act like doing crack/cocaine.

Most of the time used in a question

1. High on DXM
2. High on speed

To be very angry

i.e. mad, spazzing, angry