twisted generally related to events perceived while on hallucinogenic drugs, usually referring to an individual.
"Man, last night I dropped five microdots and ran up primrose hill naked! Boy was I tweaked!"

"I was out for a stroll on primrose hill last night and I saw a naked guy running around. He looked HIGHLY tweaked!"
by Simon November 09, 2004
girl- omg you got tweaked?!

girl- omg he tweaked you?!
by J April 06, 2005

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