Coined in the Scorsese film, 'Mean Streets', meaning a arsehole or loser.

A generic derogatory term. Many attempts have been made to define it, but it's used too widely to pin it down.

(noun) 1: A male adolescent or young adult exhibiting an unpleasant, self-centered attitude, formed during a sheltered upbringing. 2: One who revels in their own ignorance.

n. Italian-American short form of malook, motherfucker 1. a person of little social standing, one not worthy of respect. 2. an affectionate term for a regular guy, one who is unpretentious. 3. an incompetent person.

A term coined by Douglas Rushkoff in an episode of PBS's "Frontline" entitled "The Merchants of Cool." Mooks are archetypal young males(teens-early 20s) who act like moronic boneheads. They are self centered simpletons who live a drunken frat-boy lifestyle(or are frat-boys). Examples can be found anytime someone watches "Jackass." Rushkoff claimed that the media glorifies this ideal and stifles natural self expression, however, some people might argue teenage boys have always acted like morons(its actually a long-standing stereotype). Nonetheless, standardized conformist dumbass-culture behind a veneer of exhuberance is a scary notion indeed.

Opposite of Mooks are Midriffs; oxymoronic innocent skanks who are modeled after Britney Spears.

mook (mōōk)

n. Slang
An insignificant or contemptible person.
"mook." The American Heritage® Dictionary of the English Language, Fourth Edition. Houghton Mifflin Company, 2004. 17 Jul. 2009.

dummy, idiot, retard, loser, unlikeable person, poseur, etc.
Basically someone that you think is stupid.

This is how it is interpreted in So.Cal. for the most part.
There you go you fuckin' mooks.