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1.
Used when something bad happens to you like if the pop machine runs out of your favorite soda or when you're car won't start. Meant to convey your unhapiness about what has just happened and to blame whoever is responsible.
Friend 1: Hey, did you know that walmart doesn't carry that organic body wash you always use?

Friend 2: THOSE BITCHES!
by It's Bailey Bitch!!! May 02, 2010
 
2.
Those girls that spend their time thinking of ways to insult you and start rumors about you. Even though you're nice to them 24/7 they still treat you like piece of shit.
Stacy: Omg did you hear that becky is lesbian?
Tess: No she's not I know that for sure. One of those bitches probably made it up.
by blahblahblahblahblah1234445678 April 02, 2013