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In "Homer Goes to College," Homer gleefully sets his high school diploma aflame, while singing, "I am so smart, I am so smart, S-M-R-T, I mean S-M-A-R-T!" Behind him his living room is going up in flames.

The now legendary "S-M-R-T" line was actually not in the script and was a genuine error by voice actor Dan Castellaneta. However, the error was so much in Homer's character that they chose to include it in the finished product.
People now chant either "S-M-R-T" or "I am so smart, S-M-R-T", particularly when they're feeling stupid, celebratory, or both.
S-M-R-T by Kaleah November 3, 2005
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S.M.R.T. 

A nice way of saying that someone is so stupid, that they don't even know how to spell smart.
"I'M S.M.R.T.! YAAAAAY!!!"
S.M.R.T. by LAURENANDCHELSEA May 11, 2006

s.m.a.r.t. 

super manly and ridiculously tricked-out

acronym used when describing guys that make nerds feel bad about their intelligence.
Steve and Tyler are so s.m.a.r.t. they have bright futures and hot girls.
s.m.a.r.t. by THEEMisterC June 14, 2011
An Acyronym for: Sexually Molested, Ass/Anal Raped twice
Two plus Two is Nice
-Boy, your s.m.a.r.t
Hey, Thanks!
S.M.A.R.T by Ramer November 3, 2007

s.m.a.r.t. 

S-Sexually
M-Molested
A-And
R-Raped
T-Twice
Man that guy is the .S.M.A.R.T.

S.M.A.R.T. 

An acronym for Surveillance Marketed As Revolutionary Technology.
S.M.A.R.T. homes use the Intenet of Things to keep tabs on what you watch, buy, like, and dislike.
S.M.A.R.T. by Irukanji May 27, 2019

S.M.A.R.T. 

An acronym for Sex, masturbation, anal, rectal, tits. It's a machine used for self-pleasure. Mass production of the S.M.A.R.T. began in the early 2000s, and still continues today.
Hey, look at that guy using his new S.M.A.R.T. !
S.M.A.R.T. by David Lenins September 8, 2007