A unit of measurement of bactericidal/alcohol iso wipes (typically several clumped together)
1. Oh no! i just wanted one iso wipe, but i accidently pulled out a knob of iso wipes

2. Hey can you please pass me a knob of iso wipes?
by Pierre Montgomery January 28, 2009

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A slut. Everyone uses the knob on a door, just like everyone uses a slut; thus, sluts=knobs
That knob's pussy was so loose i couldnt get my dick up.
by your-just-jealous July 14, 2008

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The knob. A place in Hamilton, Ohio close to five points.

Knob is an acronym for Keep Niggers Off Block

-or-

Kill Niggers On Block
Fucking NIGGER, gett of the knob!
by Jerry_is_THE_BEST January 31, 2008

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1. A penis that is constantly erect.
2. A person who resembles a penis in physical appearance and/or behaviour.
You'll take out someone's eye with your knob sticking out like that.
by Samantha Fox December 16, 2007

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A reference used by the supporters of Crystal Palace FC to describe another set of South London supporters, the Charlton fan.

For years, the Charlton supporter (or Clown as they are commonly known) has tried to bait and bully their way into a rivalry with their neighbour (who already have a deep and ancient rivalry with Millwall FC and Brighton & Hove Albion FC) but the worst insult anybody could think of on the Crystal Palace side was 'knob' as the Palace supporter really cant bring themselves to hate them.
Look at that Clown knob trying to pick a fight with that caravan salesman.
by Jay Simon September 18, 2007

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for a male to recive oral sex from a women
im tryin to cop some knob tonight
by the real knob August 30, 2005

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Official designation for freshman cadets at The Citadel. Called such because their shaved heads resemble shiny door knobs. Of course, that is what their Public Affairs Office wants you to believe. After reading some of these definitions, I am beginning to wonder. Perhaps sending my baby boy to a military college that calls him a knob would not be wise... Hmmm...
John was shocked to learn not only the true definition of a knob but that as one, he would be expected to assume certain unpleasant duties...
by Houston September 26, 2003

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