I hate Farmville, Mafia Wars and don't have any plans on starting a fake fish tank, so I did a Facebook Flush so I don't have to see my wall cluttered with that crap!
In a collective effort, facebook friends of one person steal and adopt his/her profile picture, and each tag the original owner in their new pic. Then the group then likes and comments on everyone's new profile pic, ensuring a barrage of notifications for the target person. Works much better if the adopted picture is in any way scandalous.
Last night while Matt was out to dinner with his parents, 10 of us got him with a facebookflashmob. His phone must have buzzed non stop with notifications!