1)A punishment for bad behavior in prisons. Subject is placed in a cell with no contact with other prisoners.
2) A precaution used to prevent the spread of contagious diseases. Anyone suspected of carrying a disease is placed in an isolated room with minimal direct contact with others.
A complete dumbass. Someone unworthy of the title retard.
<PersonA> Hey, I went to this club the other night and pulled this right stunner. It was only when we got into the back of my car for some lovin when I felt something slippy and long in 'her' panties.
<PersonB> Hahahahahahaha! Fuckhelmet!