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A person holding an alcoholic beverage in each hand. Often seen at keggers, ball games, or other places where the line for a drink is rather long. Individuals will often get two drinks at a time. When one is finished they get back in line. They can then enjoy the second beverage while waiting. That way they never run out and risk ruining their buzz.
Guy #1: Dude, are you two fisting it again?
Guy #2: Hell yeah! It takes 20 minutes to get a beer in this place.
by Wiseman July 14, 2006
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1. Fisting one body cavity, with two hands. 2. Fisting two body cavities, with one hand each.
1. My wife love's it when I am two fisting her pussy.

2. I love two fisting my skanky neighbor, anally and vaginally. I rule!
by Cunty Fresh Fanatic October 30, 2010
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