To be extremeley drunk; twisted
"Damn girl i went to the club and got twazzled off them long island iced teas"
by Foxy B. March 2, 2005
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To use a public washroom inside of a high school, more precisely a catholic school. To pleasure yourself with the use of masturbation. The twazzle has only been spotted twice! Many users of the twazzle do not believe it is wrong.
When J.A.H had to really really do it! The twazzle takes place on the holyest of days.
by Twizzle Twazzle November 24, 2006
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word with no meaning. extremely fun to say when drunk/high...created out of randomness by my friend Tselar. you know you wanna say it.. go ahead. Twazzle.

also; Fo' Twazzle Muh Nazzle
Brandi When Drunk: ya know what?
Sean: what?
Brandi: Fo' Twazzle muh Nazzle.
by Bittie July 11, 2006
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A derivative of the word "Twat" that describes the pussy of a fat, over-sized women or a slut
Guy 1: "Dude check out Taylor"
Guy 2: "Dude are you high??? She has a fucking Twazzle!!
Guy 1: "Whoa... sorry, I missed her muffin-top"
by SkyHigh10 February 25, 2011
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A group of friends who gets saucy together
Look at them boyz sauced up them boyz twazzle life , aka direcktionz , banga and breeze
by NanDaMan March 14, 2017
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somebody who likes to finger twats/vaginas
hence the term
OR
they are a twazzle finger because their fingers smell of cum etc.

-extremly crude, i know.
"oh dude! *smells friends fingers* oh holy shizzz since when did you become a twazzle finger?!"
by .x.-Kiran_C-.x. January 24, 2008
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