A pretty good show on Cartoon Network with an interesting sense of style, colorful animation, and unusual, often absurd comedic situations. The show often utilizes morphing scene transitions, sentences spoken in Japanese language, and loud background music that comes from the titular band. Yes, the three main characters: Ami, Yumi and the band manager Caz are all based on real people. One of it's problems is that the secondary characters sometimes share a similar look, use the same wierd gestures, and some are just too one dimensional, grotesque, and unmemorable. Some people feel that the animation is derivative to Japanese anime, while making a mockery of the style. This is disputable, as the show's style is built upon Japanese culture, but it's drawn entirely in an American studio that uses it's own animation style.
"I kinda think Hi Hi Puffy AmiYumi is good. It's genuinely original, playful and wacky, and I just love the main characters. It sure has flaws, but I can forgive them as they don't annoy me too much. I'm not a critic, I'm just having fun, and some of the maverick animation in this is stimulating, while the comedy is often so ridiculous you just have to laught and enjoy it."
by BKMorris October 16, 2006
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A mental disorder commonly experienced by mental health professionals wherein an unshakable self-identification of being a giant sugary marshmallow ultimately complicates and disrupts their day-to-day routines.

Puffymallowdysphoria is frequently accompanied by extreme phobias of hot chocolate, fishing hooks, and people who love to make S'mores.

Additionally, sufferers of the disorder are obsessed with sexual fantasies about The Stay-Puft Marshmallow Man, also known as Mr. Stay-Puft. The fictional character from the Ghostbusters franchise frequently appears to those who acquire puffymallowdysphoria in various BDSM scenarios. Usually as a giant, leather clad, horny marshmallow.

The DSM-5 defines puffymallowdysphoria as a currently untreatable disorder. Citing the reason for no existing form of treatment as, "those who acquire the disorder of puffymallowdysphoria are the mental health professionals responsible for treating puffymallowdysphoria and other related imaginary illnesses."

Puffymallowdysphoria is derived from the Greek words ζαχαρωτό μαρσμέλοου meaning marshmallow and the Dothraki word "δύσφορος (dysphoros), meaning a profound state of unease. In Ewokese the disorder is defined as puffy-mallow-head and is believed to be caused by neurotic thoughts about a persons self importance.
Puffy-mallow-dysphoria

A. Damn! That's the third psychologist I've lost to puffymallowdysphoria.
B. I'll get the graham crackers and chocolate.
by Wittyhandle September 13, 2021
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it's like a show with to rock stars who are japanese and bad stuff is always happening to them and the animation is really crappy and the story line kinda sucks but then it's made for like little kids who will watch anything.
me: hey have you seen that one show on cartoon network?
chibi-san: what's it called?
me: hi hi puffy amiyumi.
chibi-san: yup it's really retarded.
me: yeah.... hey want to watch Fullmetal Alchemist?
chibbi-san: yeah that sounds cool
by mizu June 21, 2006
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What I have a burning sensation in.
"What should I do when there is a burning sensation in the yellow puffy part of the penis?"
by Vulgar Clown August 21, 2003
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The frothy mixture of semen and saliva that results from pushing someone's cheeks together after having received ejaculate in the mouth and not swallowing.
A puffy coat is somewhere between bumpercoats and cast iron
by zenodotus November 14, 2012
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Worthless corporate folks, aka overhead costs, with zero real world success.
Those corporate folks who walk around all day in their puffy coats with an Ogio backpack and a Yeti cup while they send emails and PowerPoints yet accomplish near nothing.
by TheTrueTexan July 29, 2022
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