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1) Contagious vaginal irritability
2) When males act like wimpy females
1) Mom, I need you to call me off of school. I seem to have a severe case of's spreading like rapid fire and I don't want anyone else to catch it!!!
2) Me and Dooch wanted to go to Walmart to ride the bikes, but our pussy of a friend Michael was opposed to the idea. He must have had a hint of muffitis.
by Jason March 27, 2005
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Unlike what the name suggest, this is not an inflammatory condition. The term is used to refer to people who always complain and have a general negative attitude toward self and others. Verb: muffing.
He is always muffing , i think he had Muffitis.
by Muffing July 26, 2018
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