The mass-energy equivalence was one Albert Einstein's most famous work and caused him much celebrity. As such, E = mc² came to mean a formula for success.
Cameron Mitchell: Even if the valley wasn't filled with Jaffa, we could never have made it to the gate and dialed out in under . . . ten seconds.
Martin Lloyd: Good. See, that's why we're here. So what do you think, thirty seconds? Maybe not such a round number. How about . . . thirty-eight!
Daniel Jackson: What difference it does it make? I mean it's not like you're going to have an actual ticking clock on the screen.
Martin: That's brilliant!
Daniel: That's ridiculous.
Martin: Trust me, jeopardy plus ticking clock is box office. It's the E = mc² of the entertainment world! Ask any executive.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.