The "dumbest girl you will ever meet" in the movie Mean Girls. She is a plastic and has espn. Her breasts can tell if it's raining. She can't spell "orange" she makes out with her second cousin, she asked Cady Heron "If you're from Africa then why are you white?"
"This is Karen Smith. It's 68 degrees and there's a 30% chance it's already raining!"
by Brie AF March 18, 2016
A dumb blonde whore who makes out with family members
Omg she made out with her cousin what a Karen Smith .
by Tati S January 27, 2016
One of the plastics in the movie Mean Girls. Is described by Damien as being "one of the dumbest people you will ever meet". Claims to be able to predict the weather using her breasts. Played by Amanda Seyfried.
"If you're from Africa, why are you white?"

- Karen Smith, 2004
by Thats16myboi July 24, 2020