Contrary to popular belief, homeboy along with homie were both created by Chicano aka Mexican American Pachucos from the word "Hombre" which is spanish for "man". It all derived from the slang they used known as "Calo".
Chuco #1: What's happenin homie??

Chuco #2: Just kickin it with my homeboy.
by rob-g April 14, 2007
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home boy to a girl is a great friend who has her back and is real too the end
johnni noi from the big d is ka8e babybez homeboy.
by opitsindrumn0120012small September 4, 2015
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In the California Prison system a "Homeboy" is someone from the same race and county you are from whom you are on good terms. Your "Home" town etc
Have you met Dan yet, he's also from Sacramento, he's one of your Homeboys!
by Dan-G-erous July 21, 2011
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A friend from the same area or town that you are.
Trey? Yeah he's my homeboy from STL.
by Wildstallion06 June 20, 2005
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Friend, Buddy, Pal. Derivation of "hombre" (ES). See also "homie."

Yo homeboy, you gonna tag that or move over so I can get me a piece??
by Markus Arelius February 19, 2008
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A slang term for 'bro' or 'dawg'. Also shortened to homie.
He is my homeboy, yo!
Wazzup, homie?
by newyorkcity May 14, 2009
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The term "homeboy" derrives from "homie", and each of those terms have been shortened down overtime as "homes", or sometimes spelled "holmes". The term was started by Mexican-Americans living in the barrios of Los Angeles, most commonly said in East Los Angeles. The term refers to friends/companions living in the same neigborhood as eachother. Which is why "HOME" is started before boy, thus creating "homeboy".
Person 1: Aye whats happening homeboy?
Person 2: nothing just chilling, you?
Person 1: about to go to Rob's house...
Person 2: who that? is he a homeboy?
Person 1: Nah... just some foo i kick it with from Grape Street.
by Eddie.P March 24, 2007
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