The expression "has left the building" used to be reserved for discouraging fans of Elvis and Marylin not to hang around for autographs, a glimpse, or a chat with their hero, thereby informing them that their hero no longer occupies the premises and has 'physically' left the building prolly in a limo ... but now generically refers to virtually anybody and anything that has 'permanently' expired, as in dead, died, death, "passed away", checked-out, dirt napped, and can no longer pay taxes and entertain the 'troops' ... but like Frank says "that's life, that's what people say, you're riding high in April, shot down in May, but I know one thing, I've been a Puppet, a Pauper, a Poet, a King, I've been up and down, and over and out, and I know one thing, EACH-TIME, I-FIND, MY-SELF, FLAT-ON-MY-FACE, I pick myself up and get back in the race ... That's LIFE! ... -bdn-
"What do you mean she's not here?"

"Like she has left the building, man!"

"I'm Sorry, dude, but your mama's dead."
by Bozo_de_Niro August 25, 2012
Meaning the show/event has ended, this comes from the announcements that used to be made at the end of musician Elvis's concerts in order to get fans to leave the arena. Now we use this term anytime an event has ended.
Jacob (cums): Elvis has left the building (collapses on the floor).
by papermachete November 3, 2005
The term is a neologism. It was a joke 'Internet term' which was first used by "Friday Night Cranks" and has since been (rarely) used by fans of the show. It was supposed to be a common "figure of speech" used on Myspace (as told on the show) and was meant be mean, "Where do you live?" when stated. Similar to an euphemism.

The term "can I take a bite out of your taco?" was also created by Friday Night Cranks at the same time this one was.
by Eidokin November 27, 2009
The words that appear when you kill all of the elvis impersonators in GTA2.
elivis guys: Thank you. Thank you vary much.
me: (pulls out uzi)

by Is this name used? March 10, 2007
When a guy's member has exited his boxer shorts by sneaking out of the flap during the night.
Sally woke up, rolled over, and looked at Frank.

It appears that Elvis has left the building, Sally thought to herself.
by Ae5Ea8 March 15, 2015