Stands for "fuck me running sideways". Is used to express disbelief or frustration. Can be said using full terminology or can abbreviated to save time while talking, texting or typing.
Person 1: "Did you remember to bring the notes for today's pop quiz?"

Person 2: "FMRS! I forgot them at home!"
by nOneXs!SteNT December 03, 2010
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"He forgot to call Again. FMR"

"I saw your girlfriend with a couple of guys at the bar last night." "What's new? FMR"
by FMRgirl January 18, 2012
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