A kindly way of saying that one is stupid. Certainly much nicer than calling someone a fuckwit, anyway.
"You dufus! Click the Print button if you wanna print, not the Close button!"
by Mr Ben February 10, 2005
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short for dumb fuck, a person that messes up all the time
"You are such a dufu, can't you do anything right?"
by ldml April 04, 2008
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Dumb Ugly Fucked Up Soldier/Sailor

Was in the lexicon long before doofus
"He's such a dufus"
"I don't think he's a Soldier nor a Sailor"
by Dufus Bill April 11, 2007
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