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1. to lose ones testicles, ball, cajones, etc. in the literal sense. Often the result of poor medical procedures or attempted home remedies for AIDS.

2. to lose the ability to go "balls out". Most common with men who are the victims of overpowering women or succubuses.
Where is Ian?

He's undergoing detesticlization by Felicia right now, they went shopping for dresses
by ianmcfians lover June 15, 2008
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