A drug not available because if you try it once you will die. Your face will melt off and your children will weep over your exploded body.
Josh totally OD'd off one hit of some Charlie Sheen last night.
by head4 March 1, 2011
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To CharlieSheen, (verb) has quite a few meanings. It can mean to generally be erratic, to bang everything including but not limited to dirty hookers, classy hookers, 7 to 30 gram crack rocks, alien heads (yes cause you are on that level), to operate in one speed, one mode, one gear, to party so hard everyone else looks like droopy eyelided armless children, to harness focus, forget normalizing, and generally just lay the smackdown on life!
"Hey, man! I got that tiger blood" "Oh, so you're parents charlie sheened a tiger?"

"Say man, I gotta couple hookers last night and charlie sheened the hell out of them!" "Isn't that illegal?"

"I charlie sheened can't and can't is the cancer of happen therefore blinking my eye and curing my brain is the negative influx of all terrestrial tiger blood beholders"
by InlowOuthigh March 9, 2011
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A drug that if you try it once you will die, Your face will melt off, And your children will weep over your exploded body.
I'm on a drug called Charlie Sheen
by epicwinwinwinrar March 11, 2011
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Verb. The action of taking more cocaine than the lethal dose of a normal sized, middle aged human could take, and surviving.
Did you hear? Gregg did a Charlie Sheen last saturday! He's lucky to be alive.
by garunas March 14, 2011
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A powerful yet undetectable drug.
After passing a drug test and ranting on a morning talk show Charlie Sheen said, "I am on a drug - it's called Charlie Sheen."
by Elliott InSpace February 28, 2011
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