The plague was a deadly disease. If you got infected by the bacteria, you would die. Obviously you don't want to die. So if you avoid something like you would avoid the plague the plague, you really, really try to avoid it.
That man I avoid like the fucking plague.
by Foxyflower September 22, 2015
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An ill-advised mantra math-anxious folks unquestionably take to heart on hearing it from negative or unhelpful people, who are only contaminating the minds of their listeners with fake mathematical information.
To tell someone to avoid pi like the plague is like telling them that π is a rational number because it can be expressed as the ratio of a circle’s circumference to its diameter.
by MathPlus November 06, 2021
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