1. The breakdown of life in space. An astronaut losing all hope and feeling that his/her return to Earth will not make any kind of difference to anyone.

2. Track 10 on the self-titled album by blink-182. A truly amazing song.
Floating above Earth alone in the car-sized space capsule, the astronaut began to doubt that anyone cared about him and contemplated never returning.
by Samson473 May 1, 2005
Get the asthenia mug.
The progressive weariness and public despair caused by a never ending series of poor, ill-informed decisions, infantile self-serving policies and generalized, narcissistic, ineffective hyperbole.
ANOTHER government shut-down! There is no way that Congress and the citizens of the USA will permit this to happen...all sides have reached Trump-asthenia to the max...
by YAWA February 11, 2019
Get the Trump-asthenia mug.