A disease a zhane has. If a zhane is a girl and is annoying, a hoe, a bitch, or something along those lines, she has zhane disease. Do not touch anything she touches or you can get it too.
Jimmy: "A zhane touched my arm. That is disgusting. I think I have zhane disease now."

Ben: "Tuff"
by Dr. Child December 5, 2018
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a girl who loves arab trappers with big dicks
zhane loves N
by realdefoyhyh February 5, 2022
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Zhane is a very rude girl. They constantly get defensive and are rude to people around them as a coping mechanism to handle their own insecurities. They are insecure in their looks and you have to help them because they are at a disadvantage because of this. They like to bring other people’s confidence down to feel better within themselves although it doesn’t work because their not even good at manipulating people even though they try their hardest.
Guy 1: she’s acting like a zhane

Guy 2: aghhhh I hate people who act like a zhane it’s the worst. Their so negative
by Mehanna May 30, 2019
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