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Your Only Squirt Once
I screamed YOSO while I jerked off in my girl's hair while she was sleeping.
YOSO by FabledPoet October 24, 2012
Related Words
You Only Stick Once. The process of hitting on multiple people knowing that you will at least hook up with one of them. The genesis of this acronym comes from the expression, "Throw enough shit against the wall and something is bound to stick."
I just tinder messaged 50 girls. At least one of them is going to be down. #yoso
yoso by aro8888 August 20, 2014
You Only Sting Once

A famous saying for bees who have the urge to sting someone
Bee 1: Ugh, I'm pissed. I wanna sting a bitch.
Bee 2: Be careful. YOSO, you remember?
YOSO by MooMooMooMOOOO June 22, 2017
You only slide once. Termed for when you go on waterslides at waterparks and perform dangerous stunts and tricks on them. This usually occurs on rather large slides, with quite a bit of height.
"Jack is about to go down that giant waterslide while standing up!"
"YOSO, Jack! YOSO!"
YOSO by Brownie724 September 14, 2012
The love child of "yo" and "so". Used to catch a peer's attention when one is about to say something important. Often capitalized when the shock factor of what the speaker is saying exceeds lowercase letters, becoming YOSO! When one is expressing concern or wary, they might draw the letters out to resemble "yooooossooooo". Derived from the popular comedy duo Jake and Amir. May also be used as a greeting between two friends.
Nicole: Yoso my cat threw up in the bong water.
Diana: Ugh, tits.

or

Amir: Yoso, when it snows my feet, they bleed coz my shoes have holes and I can nay afford socks'o.

or

Randall: YOSO PARTY AT MY PLACE TONIGHT!

or

Friend #1: Yoso
Friend#2: Yooosoooo I have a test tomorrow and I'm not ready!
yoso by nicomeowmeow December 11, 2011
an african name, but usually people with this name don’t look african.
Yosola is so cool .
Yosola by sally may weather April 19, 2020