STFU backwards, used to put the annoyance into such confusion that s/he automatically ceases talking for a moment to process what you just said.
"...and then I totally fucked that bitch in the ear."

"Dude! Up fuck the shut!"

"...What?"
by Jack Kaplan December 29, 2009
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A very extreme form of shut the fuck up, often abbreviated as UTFS. When used there is no possible comeback and the target must accept defeat no matter the circumstances
Teddy: Matt guess what
Matt: what?
Teddy: UP THE FUCK SHUT
Matt:...fine...you win
by MrMartinIsWatchingYou November 15, 2010
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When you're in an argument and you're so pissed off at the other person that you're unable to think straight thus letting out a poor execution of an insult
"You're a gay bitch ass nigga dude"

anger builds up "erGh GrAhgh gggGGG- UP YOUR FUCKING SHUT"

suicidal tendencies build up
by That random guy thing December 2, 2018
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