Thank god it's Stephen Colbert. Used when talking about the best comedian of these times.
Guy: "I hate life. My girlfriend of 10 years just broke up with me, I lost my lottery money in Vegas, and a I woke up to 6 cats mauling my face. There's no way I could got cheered up."

His only friend left: "Oh the TV's on. Let's turn to Comedy Central."

Guy: TGISC!!!! There is a god, and he's in my TV!!
by The blind man driving. March 21, 2012
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Anagram which stands for "Thank God It's Stephen Colbert", visible in the opening sequence of Colbert's show, The Colbert Report.
It's 11:30 on a Wednesday, TGISC.
by sixeyes February 28, 2012
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