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1: Crazy as in not completely mentally stable
2: Crazy as in Funny, humorous
1) You ever seen that movie Fatal Attraction? Glenn Close character is Shot-out
2) You catch that comedy show Dave Chappelle put on, dude is funny is hell. He is shot-out
by KBoogie00 December 21, 2011
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"Out of it" or brain addled from heavy drug consumption. Referring to heroin it literally means "shot out" of a person's mind.
Don't trust that guy's memory, he's shot out.
by addictmentality May 22, 2015
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1. the sum of unpleasant physiological effects following heavy consumption of drugs, particularly alcoholic beverages.

usually seen on the face. is worse with excessive sun, smoking, poor diet and hydration practices, other physical problems/illness related, lack of sleep.

2. any part of a person's body that is particularly worn and 'used up'.
she was a student/athlete in high school but she's looking pretty shot out now.

that girl is shot out, she's slept with everyone and a few of the moms.
by thatiaintwhatisaid July 29, 2010
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V. 1. not knowing what is going on
2. lack of intelligence after day and or night of drinking or smoking or both
3. lacking sense of reality
I forgot where we were going, im so shot out.
Hey im talking to you, You are so shot out.
by Cole Lillie AKA Wap November 30, 2005
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