To run the mile means to are getting drunk. If you are only paritially drunk then maybe you only ran the half mile, or if your tipsy maybe you only ran the quarter mile. but if you run the full mile then you are considered wasted. In order to run the mile you must have running shoes (alcohol). Origin: Two men were drunk on homecoming night and had to get back home, they ended up running about a mile back to their house.
Harry decided to run the mile and ended up on the toilet all night. Mitch decided to run the mile and ended up barfing everywhere.
by The Human Noodle December 24, 2010
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When two people run off to make out for a long period of time; enough to make them look like they ran a mile.
Samantha: "Those two were definitely running a mile, they were gone for an hour!"

Jennifer: "They might as well have been running two, look at them!"
by lookissokay March 05, 2017
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Another way of saying one is pooping.

Since it takes roughly around 7-10 minutes to run a mile, to "run a mile" can be used for "pooping" instead of blatantly saying one is pooping.

One can also say "2 miles" for roughly 20 minutes of pooping and so on.
Guy 1: What are you up to this morning?

Guy 2: I think I'm going to go "run a mile". Be right back.

Guy 1: Alright, I just ran my 3 miles this morning.
by county hunter February 18, 2012
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Having sex. Based on the scientific assertion that having sex uses the same amount of energy as running five miles.
by neilta August 22, 2009
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