A word formed from a combination of 2 words: PIZZA + diaRRHEA. It's when you chow down on a pizza and instantly you get the runs. It could result from any ingredient being spoiled but usually bad meat is the biggest culprit.
I was staying in a hotel in Butte. I phoned in a pizza order, pepperoni + cheese + whatever, Chicago style. Delivery was fast. I ate one slice and instantly I soiled my drawers. I changed my clothes but soon all my clothes were crapped and I had to get on the throne fast. I had contracted a severe case of pizarrhea. When it was time to hop on the 'hound for the ride back this cute PYT dressed in pink and named Terri initiated a conversation with me. She was on the other side of the seat row, looking backwards at me. Everything was fine as long as she didn't come over and sit next to me : (

Pizzarrhea ain't no fun at all.
by I Saw U2 Live Twice February 18, 2011
Get the pizzarrhea mug.
The sudden onset of diarrhea by means of the consumption of pizza, be it bad or otherwise.
I got mad pizzarrhea from that janky corner joint the other day.
by jman3000 April 11, 2007
Get the pizzarrhea mug.
specifically:

the sickness which results from eating a pizza from one of those grimy corner joints. (note to self: pepperoni is not supposed to be green.) usually accompanied by several hours of toilet hovering.

generally:

a similar sickness which occurs after eating anything which is considered unfit for consumption in places other than sri lanka. aka food poisoning.
'no, i can't go out tonight. i got a mad case of pizzarrhea from that new thai place downtown.'
by carlton berry August 17, 2007
Get the pizzarrhea mug.