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Mr. O

A master yapper/story teller trained in the arts of yappology
Thomas won’t stop talking, he’s pulling a Mr. O
by Dr. Gabe March 6, 2024
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Mr. O'Connor

Literally the most annoying person to walk the halls of Loch Raven Technical Academy. He's secretly a tomato and has a talent for randomly stepping into a conversation with your friends and making it akward.
Kayla: Yesterday I got dress coded.

Sharkisha: Oh, it must've been Mr. O'Connor who did it right?
by Basicbitchsarah September 13, 2018
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Mr. O'Malley

Mr. O'Malleycatis an Alleycat.
That stoner is a Mr. O'Malley.
by The Waldorks July 19, 2016
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Mr. O'Brien Science Brainrot

The Mr. O'Brien Science Brainrot is a subculture, religion, manuscript, and "disease", based on the life of Russell O'Brien. Due to his high-pitched voice, a voice recorded file of a Mr. Hanky soundin ahh fella went viral within New Zealand, bringing the group into popularity.
"William and Arman's conversion to the Mr. O'Brien Science Brainrot group changed my perspective."
"The legend of O'Brien's breakout of an ISIS facility through rat atom manipulation inspired me to convert to the Mr. O'Brien Science Brainrot"
by Bigwillyoftingletribe April 24, 2025
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Mr.O

The name Mr.O is short for Mr. Orangutan (full name: Buddha Orangutan). Mr.O is a short, stocky and lovable orangutan who lives part time in both Seattle and Borneo with this chimapanzee wife and their 15 + children. He is always working multiple jobs and doing rather poorly at them. He's usually in a fowl mood and pretty grumpy but at the end of the day- you've gotta love him.
Mr.O is complaining about having a husky frame.

Mr.O is strangling his son (who is also his boss) for not giving him the holidays off.

Christmas Eve is Mr.O's birthday.
by JEYRE November 10, 2009
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Mr O'Dwyer

A Fat guy with a juicy looking double chin. That will impregnate you every time you look at it.
Damn, Mr O'Dwyer is gonna make me nut..
by bigbootywholes July 26, 2023
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Mr.O_5411

by R. August 10, 2023
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