When someone you're interested in and talking to all of a sudden stops and you have no idea why, or when they stand you up and don't tell you.
"I was really into Mari, but then she boarded Flight 370 I guess."

I was supposed to have coffee with Maxx, but I guess he got on Flight 370."
by jdod March 14, 2014
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The flight I wish you took.
You: "Hey Anon, what flight should I take?"
Me: "Malaysia Airlines Flight 370"
You: "Ok, thanks!"
by MalaysiaAirlinesFlightMH370 March 31, 2014
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"Hey, why are you so late?"
"Dude, my keys were totally Flight 370. Couldn't find them anywhere."
by J R Paulson March 15, 2014
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A sex move that consists of sneaking out of the bedroom during sex and ceasing contact indefinitely.
Molly: 'Melissa, why are you crying?'
Melissa: 'I was having sex with Brendan, and he stopped, so I turned around to ask him why, but he wasn't there anymore. He hasn't responded to my texts or calls, and no one has heard from him in a week!'
Molly: 'Sounds like he gave you the Malaysia Flight 370!'
by Big Gay Mike December 2, 2014
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Homie 1: yo dawg my dad ran away when I was all baby uno
Homie 2: so was he blick or was it a Malaysia flight 370 ting??
by Fancy shmancy sauce machinery February 19, 2018
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