A person who often purposely doesn't like something or is against it just because you show interest in it. A dwaine is also a queer who is sexually abused by his younger sibling noted by cigar burns to his ass cheeks. Dwaine is often seen as family to women it is for this reason he can't form a relationship with one. A dwaine can be noted as a trust worthy and loyal friend possible due to this they are often aceepted.
Guy: I love that shirt.
Dwaine: I hate that shirt.

Dwaine: I like you a lot
Girl: you're more like a brother to me.
by Luck916 July 1, 2014
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Guy 1: Bro stop being 'dwain'
Guy 2: what i'm just feeding the alligators with my hand
by dwainpp November 12, 2017
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When you feed a special needs person lsd and stand in a circle yelling "nightmare nightmare nightmare" until you've cured them
Hey wanna meet up later we're going to be dwaining the water from Kim's brain
by Goddess baby December 28, 2017
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n. Someone of the male gender:

romantic, tall dark and handsome, gentleman, hilarious, charming, good dancer and kisser... pretty much the perfect guy.
Sara: Who was that guy you were with?

Laura: Dwaine!

Sara: OMG, LUCKY!!!
by Mamabear24 November 21, 2021
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A cold guy until you get to know him. He's actually silly and really fun to be around. Dwaine can be clingy if he really likes you and will try his best to make you smile
Dwaine is here to support you
by ThatMintyMint November 23, 2021
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