Real talk. Serious talk. Usually between adolescent teenage boys. On occasion, "Boy to Boy" talk can be among grown men when trying to get each other's serious attention.
Example: You break your ankle jumping over a girl who you were trying to T bag. You scream to your buddy who is laughing and thinks you are kidding, "DUDE! Boy to Boy! I need to go to the ER!".
by prettyboy1000 September 06, 2016