Ai yai yai! 

can be used to express defeat, confusion, excitment, joy, anger...everything depending on your tone.

Usually indicates some kind of problem.

also a great way avoid answering questions properly and seem like you are invested in conversation.

boring person: blah blah blah blah blaAAAAhhh.
you: ai yai yai.
boring person: blah blaaaah blahhhh???
you AI YAI YAI!

Ai yai yai! by dolar001 June 9, 2011

AIYAIYAI 

An expression or reaction towards ones statement, expressing flustered feelings within oneself.

“AIYAIYAI DON’T DO THIS TO ME, DO NOT SHOW ME THAT GODLY FACE OF HIS”

AIYAIYAI by Katie Chan November 26, 2020