n. The situation whereby a medical or medical/psychiatric condition causes a "domino effect" of other dangerous symptoms and conditions ensuing.
Named after the Rube Goldberg "contraption" machine, any machine that uses a chain reaction of events to achieve a final, trivial goal (in this particular case, possibly death).
Named after the Rube Goldberg "contraption" machine, any machine that uses a chain reaction of events to achieve a final, trivial goal (in this particular case, possibly death).
After my brother had that bout with strep, it apparently got to his stomach and paralyzed it, giving him a nasty case of acid reflux, which in turn began to launch acid clear up into his throat and mouth, not only severely damaging his teeth... he's also he's worried he's going to get cancer one day from all that acid where it's not supposed to be. And to say nothing about all the dental surgeries he's gonna need... talk about a case of Rube Goldberg Syndrome!
(No really, it has happened.)
(No really, it has happened.)
by Andy Khay January 23, 2009

"Hey Tony, did you see Shawn Kemp after his career was over? If you thought he could throw it down in the NBA you should see him slam dunkin rubes."
by Shane and Tony of Club SinRock May 11, 2014

"How did the fire start?"
"Well, Mark was wasted and in reaching for his cell phone knocked over a glass, that fell on a power strip, that set the couch on fire"
"I see, classic Rube Goldberg Alcoholism"
"Well, Mark was wasted and in reaching for his cell phone knocked over a glass, that fell on a power strip, that set the couch on fire"
"I see, classic Rube Goldberg Alcoholism"
by Bourbonsauce January 21, 2010

Basically, a 'machine' that uses many ordinary items, and positions them in a way so that when activated, sometimes by 'knocking down the first domino' so to speak, it leads to a series of events that are all activated by the previous events.
They are most always elaborate, with many things going on at one time.
They are hard to build, and sometimes take over 4 months and a millions hours to build, but the results are spectacular.
They are most always elaborate, with many things going on at one time.
They are hard to build, and sometimes take over 4 months and a millions hours to build, but the results are spectacular.
Child 1: Hey, let's play Mouse Trap!
Child 2: I heard that's something called a Rube Goldberg Machine!
Teen 1: Have you seen Ok Go's new video, 'This Too Shall Pass'? It's totally a Rube Goldberg Machine!
Child 2: I heard that's something called a Rube Goldberg Machine!
Teen 1: Have you seen Ok Go's new video, 'This Too Shall Pass'? It's totally a Rube Goldberg Machine!
by loveisjujujubaby March 13, 2010

Applying mayonaise and jelly to the foreskin and or scrotum of a mans penis as lubrication for oral sex in preperation for a prostate exam
Scott Behm tryed RUBING MY SUBURBAN during our conversation on gay rights in the little boys section at K-mart.
by *suck my choad* October 11, 2008

Any liberal (voter or politician) who is either convinced or lying that there is never anything wrong with the DNC, Democratic party or any Democratic politician or liberal figure; even if they are corrupt, to the right on certain issues/policies or if they are complicit and refuse to fight for any good policies. In their minds, no matter what anyone in Democrat-name does, nobody is ever allowed to criticize them, even from a leftist perspective. They are typically anti-progressive and align most with centrist Democrats and even tend to hold beliefs that align more conservative or right-wing than their leftist or progressive peers.
Whenever any leftist critiques a Democrat for not being progressive on any certain issue, they are immediately bullied by these people and assumed that they are on the right-wing when they clearly are not. These people are also more commonly known as blue-MAGA.
Whenever any leftist critiques a Democrat for not being progressive on any certain issue, they are immediately bullied by these people and assumed that they are on the right-wing when they clearly are not. These people are also more commonly known as blue-MAGA.
Liberal: Joe Biden is perfect! He should be reelected!
Leftist: He is clearly in cognitive decline, and responsible for funding a genocide in Gaza. You’re such a lib-rube!
Liberal: How dare you! Fall in line, or else you’re with MAGA!
Leftist: He is clearly in cognitive decline, and responsible for funding a genocide in Gaza. You’re such a lib-rube!
Liberal: How dare you! Fall in line, or else you’re with MAGA!
by techyartsyman52 September 11, 2025

girl 1: hey , i heard you got mad game last night!
girl 2: yeah, but he had crazy ass rubes :/ i'm still finding them everywhere!
girl 1: that sucks dude :/
girl 2: yeah, but he had crazy ass rubes :/ i'm still finding them everywhere!
girl 1: that sucks dude :/
by mozzieblanket May 27, 2017
