When your on a roof drinking beer being a dickhead, than you try be Tony Hawk only to fall on ass, while a little fuck gives you the finger, a fire to your right and a fat pig just being a pig in the background.
someone who is definitely drunk and/or completely under the influence of one or more drugs beyond the point of comprehension, rationality and all response. They have already met their limit and know they have met their limit but will not stop. They are definitely puking everywhere and are behaving abnormally, influenced by whatever's in their body. They must not let their heart rate get low or they’re at risk of their body shutting down completely.
The other day my friend got so plaster fucked with multiple drugs that he was at the verge of shutting down completely and dying.
When someone has been taking drugs for so long that their brain is fried and they look like a washed up junkie. Not to be confused with stoners.
John: Hey man, the other day I ran into that guy Joe who we went to school with.
Jack: Oh yeah, how is he?
John: Not too good. He's totally drug-fucked.
Jack: That sucks.