I.S.H. 

Incase Shit Happens .... Fairly Simple

What Do You Need That Insurance Plan? Your 21.

For I.S.H.

I.S.H.?

Incase Shit Happens.

I.S.H. by Derek Silvers September 8, 2005

I.S.383 

A school where most girls there are treeshes, and school thots, while the boys be acting gay asf, and makes you swear they ain't gay. Most teachers be yelling and be teaching you almost nothing that's gonna contribute to your career.

Person 1: "I wanna go to I.S.383! It's a gifted and talented school right?"

Person 2: "DO NOT GO THERE. Only go there if you want the girls to act retarded and shit. You could look at their snap and see the retarded shit they post. 'Inspirational' quotes, men and women crush days, and duck mouth selfies."

Person 1: "Oh ok I change my decision."

I.S.383 by AnonymousX_ November 14, 2019

I.S.S. 

Imperial Star Ship

Prefix used by the Terran Empire; from the original Star Trek episode "Mirror, Mirror";

Computer: "...succeeded to command of I.S.S. Enterprise through assasination of...."

I.S.S. by WitnessX June 20, 2006

I.S.W.S.O.M.B.R.H.P.

Iis - wom - burp

If. She. Was. Sitting. On. My. Bed. Rubbing. Her. Pussy.

Guy #1: "Dude would you bone that chick?
Guy #2: "If she was sitting on my bed rubbing her pussy, then yes"

Guy# 1:"Yo Look at that girl... I.S.W.S.O.M.B.R.H.P.?"
Guy# 2: (nodding his head) "iswsombrhp."

I.S.W.S.O.M.B.R.H.P. by Mrdoumass May 25, 2009

I.S.H. 

Incase Shit Happens .... It's That Simple

Friend- Why Do You Carry That Knife.
You- For I.S.H.
Friend- I.S.H.?
You- Incase Shit Happens
Friend- Ohhh

I.S.H. by Fuji Jin September 24, 2005

I's the shit 

After smoking weed and getting high. One enters the realm of social networking with friends and starts a conversation exclusive as of containing the word "I" followed by any other word. The receiver of these messages should replying in the same taste following these simply rules. These conversation may stretch to any point as long as the rules are never broken. The conversation may last indefinitely.

"I's the Shit"
High Guy #1: I laugh.
High Girl #1 :I smile.
High Guy #1 :I love
High Girl #1: I admire

ETC...

I's the shit by BinaryTakeout January 26, 2010

i.s.a.f.r.i.l. 

this stands for..... "i'm such a f**king retarded idiotic loser! it is pronounced eye-is-a-frill.
also i.s.f.r - i'm so f**king retarded.

emily: aghhh!!
jake: sup??
emily: i.s.a.f.r.i.l......i've done it all wrong ill have to start over!!!

i.s.a.f.r.i.l. by Tango_Whore November 29, 2005