the african proverb derived from our brother.. SNOOP DOGGY DOG
It means for sure ma brother
DUde- yoyo dawg what's crack a lackin
brotha-nothin
dude- so you wanna go hang with shaleesha and shaquinta
brotha- Fo SHizzle My Nizzle
by YoBrotha from Anotha Motha November 23, 2005
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For sure my nigga...
Should only be used by NOBODY.
Whitey 1:Are you going to shut the fuck up tonight?
Whitey 2: Fo' shizzle my nizzle
ME and my sword: DIE YOU FUCKING MORON

Blackey 1:Ya gonna B gettin wit dat ho dis night mah also ignorant N dupid nigga?
Blackey 2:Fo' shizzle mah... <abrupt stop because my sword just lobbed his head off>

Me: Please Suge kill yourself
Suge: aight foo I done already been trien to do dat fo ya see I is in da hood an I's dun no how ta do tings right, werd.
by Nataservant June 30, 2004
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The direct translation of this slang word is "for sure my nose"
fo-for
shizzle-sure
my-my
nizzle-nose
Thomas: Dang, this shit is crazyyy
Kelly: Fo Shizzle My nizzle
by kellywellykinz June 5, 2009
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used to express feelings of concurence meaning sure my nigga.
person1: whaz up nigga?
person 2: nuttin dogg.
person1:u wanna go smoke a jizzle?
person2: fo shizzle my nizzle.
by bob April 16, 2005
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