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Rule One 

Literal translation is 'don't be a pussy'. Most often used when berating someone with 'you forgot rule one' implying that if one has forgotten rule one then they're indeed a pussy.
Dan: I'm a little tired, my boots are chaffing and the wind is blowing in the wrong direction.
Gora: You're in violation of rule one. Get over that kicker.
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In the UK prison population, Prison Rule 43 says that an inmate can request to be segregated from the main population, "for their own protection", or when deemed necessary by the prison authorities, to maintain "good order and discipline."

Segregation is not necessarily isolation as there is - in most prisons an entire wing occupied by those prisoners "on the Rule" or "doing the numbers. " A wing full of segrated inmates can often amount to hundreds, so isolation wouldn't be an issue.

People going on the Rule would probably be convicted police officers, prison officers, judges, sex offenders, clergy and anyone of celebrity status or in public office to name but a few.

The life of a prisoner on a segregation wing or unit, is supposedly better/easier as there's much less violence, aggression and confrontation, due to the permanent threat of being instantly transferred back into the general population.

Prison Rule 43 is more commonly requested by the inmates rather than enforced by the prison authorities.
I want to go on the Rule 43
(I want to be segregated)
NOTE The (43) above wouldn't be spoken. I had to add it to comply with the reference to the word being described
Rule 43 by Meltham Man June 16, 2018
Related Words
Rule 34 Rule Rule 35 rule 1 RULE #1 rule 2 ruler Rule 11 rule 43 rule 69
RULE #1
no. fat. chicks.
RULE #1 by brennasty April 5, 2009
If you find a girls dildo, you may use it on her.
Girl: "Oh my god, that's my toy!"
Guy: "Rule 146"
Girl: "Fine."
rule 146 by Resizepixel January 22, 2014

Rule of the 3 "R's" 

Rent DvDs
Ripp DvDs
Re-sale DvDs
Ex:

Go to any place that rents movies, rent some, slap that shiet into your computer and start ripping them. There you go, no need to pay $20 for DvDs anymore.

How to do it you say? Find out yourself biaatch!
In Wonderland, a rule of the Queen of Hearts' court stating all persons more than a mile high must leave the court immediately.
King: "Rule 42, all persons more than a mile high must leave the court immediately!!"

Alice: "I am not a mile high, and I'm not leaving."
Rule 42 by Disnevytte August 30, 2010

Rule 34.5 

If it exist's, there is a pony variation of it.
Person A: "What if there was porn, but with ponies?"
Person B: "Rule 34.5"
Rule 34.5 by HAZARD78 November 29, 2011