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Duff Chuff

basically getting a girl up the duff and then sucking the baby out through a straw when possible
i fucking did the duff chuff to chelsea leigh last night
by ryan926 January 12, 2009
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duff

That 3rd girl is definitely the duff of the group.
by G January 2, 2004
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Duff Mckagan

Former GnR bassist. Adorable in the early eighties but kind of bottomed out in the early nineties. His pancreas exploded due to, too much heavy partying and too much drink. Great bassist though, and he's looking real good right now.
Damn son! Duff is looking fine in the 'Slither' video!

Damn that boys pancreas got Duff'd
by Blurgh May 3, 2005
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Duff

A real term used in the heydays of Cocaine frenzy, 70s, 80s. Duff refers to that portion of your cocaine that consists of powder only, usually full of cut or anything else but real cocaine.
Shit, I won't buy from that dude again, this is all duff.
by Gojai August 30, 2017
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I-Duff

Irritating
Designated
Ugly
Fat
Friend
or (I-DUFF)

The new and improved Apple trademarked iDUFF to irritate the fuck out of everyone!

Similar to a dumb bitch and even more similar to the everyday DUFF, but irritating as hell.
A dumb bitch who comes who college dorm uninvited to hang with her roommate while her roommate is visiting her boyfriend at another college and who just wants a little poontang. The I-Duff not only cockblocks said boyfriend, but annoys every fucking in the building through the following: 1) Bitch yells to everyone all the fuckin' time how she loves you 2) Bitch somehow learns your name, even though you and previously mentioned boyfriend haven't mentioned it 3) Does dumb shit all the fucking time to irritate the hell out of every soul around her, thus causing everyone to be pissed off 4) All of the duff traits are fullfilled, thus not even making for a nice bust-a-nut night with any guy around while his roommate is gone
by Smith 105 January 20, 2009
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Haylie Duff

Hilary Duff's ugly older sister who's face resembles the mask from the movie Scream.
Haylie Duff is known as the Ugly Duff for a reason. That HUGE nose and chin!
by fags-in-the-shower May 18, 2006
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Fluff A Duff

Super fluffy powder that's very good for skiing. Gnar pow pow.
Nice, bruh, I have those too; they're super good in the deep, deep fluff a duff.
by WeelAfterbangs January 19, 2011
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